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Injection Site Reactions Mild redness, itching, or tenderness at the injection site Usually resolves within 2448 hours Rotating sites (abdomen, thigh, upper arm) and allowing the pen to reach room temperature before injecting reduces reactions Serious Side Effects When to Call Your Doctor Immediately These are uncommon but require immediate medical attention

By combining symptom pattern, blood tests (rheumatoid factor, anti-CCP, CRP/ESR), and imaging

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This is often where individuals begin to notice more significant changes in appetite

Elevation: Use a wedge pillow to keep your head and chest slightly elevated