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The LEADER trial with liraglutide and the REWIND trial with dulaglutide did not show significant increases in retinopathy complications, though differences in trial design, patient populations, baseline retinopathy prevalence, and rates of glycemic improvement may explain these discrepant findings

Xie L, Lu J, Ostenson CG, Xu T, Chen ZW

Monitoring: Take measurements, waist, hips, chest, thigh, and progress photos at week 5 and again at week 12

In clinical trials, CONTRAVE was administered with meals

But if you are trying to pick the compound with the better pure-science case for maximum weight-loss potential, retatrutide is the one I would lean toward