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What TRIUMPH-Outcomes will tell us The TRIUMPH-Outcomes trial is designed to determine whether retatrutide significantly lowers the incidence of major adverse cardiovascular events, defined as cardiovascular death, non-fatal heart attack, and non-fatal stroke

Furthermore, semaglutide treatment resulted in a significantly higher percentage of patients with NASH resolution than placebo in the phase II trial involving patients with NASH [80]

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While GLP1 medications are designed to act on appetite and satiety, they dont address all of the systems involved in weight regulation