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European Radiology , 17(1), 211-219

A CobaSorb test showing a clear increase in holoTC supports a normal uptake, while an increase below a set limit should be taken with some reservation before a conclusion of a permanent impaired uptake of B12 is made

A 2025 orthopaedic sports medicine systematic review describes increasing use despite lack of FDA approval and bans in sport, and emphasizes that the evidence base is dominated by preclinical studies with limited high-quality human data

Limits to keep in mind The oral format is no magic wand

Folic Acid Supplements: This supplement may help in the production of red blood cells and is particularly beneficial for patients undergoing regular transfusions to enhance overall blood health