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doi: 10.3906/sag-1808-67 19 Almanza-MonterrubioMGarnica-HayashiLDvila-CamargoANava-Castaeda

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When administered, the peptide preferentially accumulates in adipose tissue, where it interacts with beta-3 adrenergic receptors on fat cell membranes and initiates metabolic signaling cascades

This age-related decline has been proposed as a contributing factor in age-associated changes to skin biology and wound healing capacity, though the causal significance remains an active area of research