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Patients should be aware that severe or progressive cold intolerance especially when accompanied by significant fatigue, constipation, dry skin, hair loss, or unexplained weight gain despite continued GLP-1 therapywarrants investigation for hypothyroidism or other conditions

Coadministered cagrilintide and semaglutide in adults with overweight or obesity (REDEFINE 1)

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(1998) vitamin E has the potential to modulate both tubulointerstitial injury and glomerulosclerosis, inhibit TGF- and decrease renal malondialdehyde concentration

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