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Estrogen and progesterone levels are at their lowest , and the hypothalamus responds by increasing secretion of gonadotropin releasing hormone (GnRH), which triggers pituitary production of gonadotropinsfollicle stimulating hormone (FSH) and luteinizing hormone (LH)

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(2019) 7:206.doi: 10.3389/fped.2019.00206 70 MaherB