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Right now, the data they have on how the drug may impact oral contraceptives is slim, but is listed on the drugs label to be safe

5 In summary, while Berberine shows promise, experts advocate for regulated clinical use, appropriate patient selection, and more rigorous studies to validate its safety and efficacy across broader populations

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Semaglutide is generally not used during pregnancy or breastfeeding, in people with the thyroid or MEN 2 history above, with a history of pancreatitis, or with certain other conditions