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Acknowledgements The authors thank the Vice-Chancellor for Research and Technology of Kashan University of Medical Sciences and the Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran (Grant Number: 98138)

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Also, it is now discovered that inflammation and the accompanying generation of free radicals of oxygen (ROS) can trigger tissue plasticity by reverting cells to pluripotency [ 10 ]

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