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It means working smarter with dosing to minimize digestive side effects while maintaining therapeutic benefit
This is called the ileal brake. The presence of macronutrients in the ileum, the last section of the small intestine, triggers a slowdown of the digestion process and release of appetite-suppressing hormones
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The article says the decision involves more than age or weight: providers typically evaluate BMI status, obesity-related complications, documented metabolic dysfunction, cardiovascular risk, previous weight-loss interventions, and family history of metabolic disease
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