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As mitochondria function is determined in part by mitochondrial dynamics, the balance between fusion and fission and the expression of proteins that regulate each process can participate in the preservation of cellular integrity and determine APAP hepatotoxicity (Karbowski et al., 2002

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2022 Jun 1;13(3):943-959

After a standardised breakfast, semaglutide, compared with placebo, led to a lower ad libitum (as much as desired) energy intake during lunch and during the subsequent evening meal and snacks, resulting in a 24% reduction in total energy intake across all ad libitum meals throughout the day