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Proteomic analysis of iPSC-derived organoids Organoids were disrupted in 50 L of lysis buffer (20 mM Tris, 150 mM NaCl, 1 mM EDTA, 1 mM EGTA, 1% Triton X-100, 20 mM -glycerol phosphate, 1 mM sodium orthovanadate, 5 mM sodium floride) and sonicated for (2030 s)

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PMID: 39658753 J Med Chem Design, Synthesis, and Biological Evaluation of Mono- and Diamino-Substituted Squaramide Derivatives as Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthase

Tsai WH, Chuang SM, Liu SC et al (2021) Effects of SGLT2 inhibitors on stroke and its subtypes in patients with type 2 diabetes: a systematic review and meta-analysis

Early human trial and case reports are mirroring these findings as well