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For years, I have advocated for plus-size riders, and the need for bigger cycling clothing, improved transparency on weight limits, and inclusive riding communities

If, after a serious effort, progress is slow or a patient faces clinically significant obesity, we may add a GLP-1 as an afterburner to keep momentum high

more gains

GLP-1 influences digestion by slowing down the rate at which food leaves the stomach, stimulates insulin release from the pancreas, and sends a message to the brain that weve had enough to eat. Theres great detail about how GLP-1 works but Hackett alerts readers to side effects (some severe)--and the rebound, when weight comes right back

What bac water means Bac water is the common shorthand for bacteriostatic water