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Handsearching yielded an additional seven citations, giving a total of 213 publications covering 130 unique studies for inclusion

However, NLY01, a brain-penetrant, pegylated, longer-lasting version of exenatide, provided no significant benefits in PD patients with a H&Y stage of 2.5 and an average disease duration of 1 year, as assessed by the MDS-UPDRS Parts II and III scores

3,4 In contrast, in Parkinson's disease (PD), neuronal deposits of -synuclein are present and form the primary structural component of Lewy body fibrils that are characteristic of the disorder, whereas in Huntington's disease (HD), cytoplasmic and nuclear deposition of the huntingtin protein and fragments thereof are found

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Zepbound is an FDA-approved prescription medication used for weight management in adults