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The N-terminal finger (residues 17) of one protomer inserts itself between domains II and III of its neighbouring protomer, and promotes the formation of the dimer and the S1 subsite in the neighbouring protomer 83

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The dose-response relationship of paracetamol and liver injury is in contrast to so-called idiosyncratic drug-induced liver injury, which is restricted to a subset of susceptible individuals

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Its essential to avoid strenuous activities or swimming for at least 3 days after the treatment, as sweating and pool water can introduce harmful bacteria that may affect your skins healing