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Tesamorelin causes transient increases in fasting glucose (mean +4.7 mg/dL) due to growth hormones insulin-antagonistic effects, though this typically resolves within 8 weeks of discontinuation

En un estudio de 13 semanas de duracin realizado con ratones (empleando dosis de 0, 7,5, 15, 50, 275 750 mg/kg en el alimento), se observ mayor incidencia de hiperplasia e hiperkeratosis de las clulas epiteliales escamosas del preestmago en el caso de los machos y las hembras cuando se emplearon posologas de 50 mg/kg y superiores

doi:10.1016/j.ijpharm.2023.123016 Retrieved from Jahagirdar, D

Appl Microbiol Biotechnol 102:1010310117

Alternate locations help reduce irritation