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Novo Nordisk submitted a New Drug Application to the FDA on December 18, 2025, with FDA review expected during 2026

Testosterone cypionate is a commonly prescribed form of bio-identical testosterone and is often used to treat conditions associated with low testosterone levels in men, such as hypogonadism

Notably, REM sleep deprivation has been associated with increased mitochondrial biogenesis in the hippocampus and the emergence of manic-like behaviors in rodent models (Kim et al., 2022)