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Dysfunction in endothelial cells is characterized by a reduced ability to dilate blood vessels due to decreased availability of nitric oxide, dysregulated angiogenesis, increased inflammatory adhesion molecules, permeability, and low-density lipoprotein oxidation [28]

Conflict of interest CFF and PK have a partnership interest in Ekam Imaging Inc

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Recent experimental and clinical observations [15, 19, 23] hint at GLP-1RAs acting as modulators of neuroinflammation, oxidative stress, and neurogenesis, providing a broader framework for their potential impact on psychiatric conditions