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Back Tschp, MH, Finan, B, Clemmensen, C, et al (July 2016) 'Unimolecular polypharmacy for treatment of diabetes and obesity', Cell Metabolism , 24, 51-62

Higher insulin levels promote weight gain and metabolic stress, while low portal insulin and high glucagon tend to produce post-meal hyperglycaemia and increased insulin requirements

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Cardiovascular Benefits : There is growing evidence suggesting that GLP-1 R agonists may have cardioprotective effects , with research exploring their potential in preventing cardiovascular events and improving heart health in patients with type 2 diabetes

EP/Z001803/1) and P.-P.J.-O