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The rationale is that effects accumulate during the course and persist between courses, with new courses reinforcing the previous effects

2007;293:R9837

10.1016/j.eclinm.2023.101946 45 FletcherS

6 The durability of this protection was reinforced in 2023 when a high-profile Inter Partes Review (IPR) challenge filed by Mylan (now Viatris) against the 343 patent failed