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Do not leave the reconstituted vial at room temperature between doses

The cells were then dissociated with Accutase and seeded as a monolayer in desired culture vessels for 3 days before infections

Platelet activation triggers further leukocyte activation and promote RBC adhesion to an exposed endothelium ( ex vivo studies, and was well tolerated by patients, but on a 24-month follow up, patients on the treatment arm failed to show reduction in the frequency of VOC (Kanter et al., 2019) (ClinicalTrials.gov identifier: NCT02482298)

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Br J Haematol 193:894901 Uyoga S, Mpoya A, Olupot-Olupot P et al (2019) Haematological quality and age of donor blood issued for paediatric transfusion to four hospitals in sub-Saharan Africa