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This dual mechanism produces more pronounced weight loss in clinical trials compared to semaglutide alone, which could mean greater estrogen reduction through adipose tissue loss

Reduced Inflammation: Many patients notice less swelling in hands and feet or fewer puffy dayssmall clues that internal, vessel-damaging inflammation is diminishing

Therefore, peptide analogs of GLP-1 have been developed to treat type 2 diabetes and obesity, with the beneficial outcome of lowering cardiovascular risks 10,11

One clinical study found that these tend to be mild to moderate, occurring primarily when dosage levels increased from 5 mg to 10 mg/15 mg

Gestational diabetes mellitus, hypertension, and dyslipidemia as the risk factors of preeclampsia