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[] GLP-1 RAs also play a role in central appetite regulation, leading to reduced food intake, and have direct cardioprotective and renoprotective effects, making them beneficial for both CV and renal health in patients with T2D

Gastrointestinal side effects like nausea, vomiting, and constipation occur in both medications but tend to be more pronounced during semaglutide's titration phase due to its stronger receptor activation

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