Additionally, modern biotechnologies have enabled the identification of interactions between Chinese medicine components and target proteins, providing a solid theoretical foundation for their clinical application [238]
For example, type 2 diabetes increases FA uptake and oxidation in the heart (Rijzewijk et al., 2009), high salt-induced cardiac hypertrophy was associated with no changes in FA metabolism ( FABP3 , which mediates FA transmembrane trafficking, was downregulated, while CPT1 , which mediates mitochondrial transport and -oxidation, was upregulated
Puig et al., 2015)
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