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With the tail-vein injection, rAd-GLP-1 was detected in pancreas, liver, spleen, heart, and lung, that is to say, all over. In the current study, rAd-GLP-1 was placed where it belongs, that is into the duodenum

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2838 Although there is no evidence that AMPK directly phosphorylates PPAR to influence its transcriptional activity, AMPK acts to increase both the expression and activity of PPAR coactivator-1a (PGC-1a), which serves as a coactivator for PPAR as well as for several other transcription factors that promote mitochondrial biogenesis

doi: 10.1016/j.soard.2019.06.022 16 JerlhagE.EgeciogluE.DicksonS