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There hasnt been extensive research on vitamin B12 to treat sciatica, but at least one study has shown promising results

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WELLNESS : This vital vitamin also contributes to overall wellness by aiding in red blood cell formation, improving metabolism, and supporting nerve health

Mouth and Tongue Pain You also may benefit from B12 injections if your tongue is red, inflamed, and painful or if you have inflammation or sores in your mouth

Improving mood and memory: Studies suggest B12 may play a role in mood regulation and cognitive function