cagrilintide with semaglutide Cagrilintide–semaglutide (CagriSema) as an add-on to basal insulin in adults type 2 diabetes (REIMAGINE 3): a randomised, double-blind, placebo-controlled, multicentre, phase 3 study In the REDEFINE 1 phase

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High-fat or high-sugar meals whilst not contraindicated, these may worsen gastrointestinal side effects, particularly during the dose escalation phase

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In comparison to placebo, liraglutide treatment reduced the prevalence of NAFLD by two-thirds, the amount of fat in the liver by 44%, visceral adipose tissue by 18%, and body weight by 5.2 kg (5.6%) (199)