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doi: 10.3390/ani10122455 207

The NHS reports that severe calorie restriction, such as with anorexia, bulimia, or similar eating disorders, sends a message to your brain to stop producing the hormones needed for ovulation (and if you dont ovulate, you wont have a true period, though you may still experience some vaginal bleeding)

brief excursions for dose preparation are acceptable

Oral lipoic acid supplements are better absorbed on an empty stomach than with food: taking lipoic acid with food (versus without food) decreased peak plasma lipoic acid concentrations by about 30% and total plasma lipoic acid concentrations by about 20% (8)

Wang, Z., Hop, C