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Finishing dinner a little earlier or delaying breakfast slightly can be enough to create the window and many people find it naturally reduces late-night snacking too

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Contrave is already a combination drug, with the active ingredients bupropion and naltrexone, which are not individually approved for weight loss but work together to aid in chronic weight management

The experimental drug Apabetalone (RVX-208) in clinical treatment for prediabetes inhibits BET proteins and prevents them from binding to acetylated histones, which reduces the expression of genes involved in lipid metabolism, inflammation, and plaque formation in arteries (19)

Incorporating these into your meals and snacks can help bridge the gap if you struggle to drink enough water