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Specific ROS (colorimetric or fluorogenic substrate-based methods): 1

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By activating MC4R, PT-141 stimulates pathways involved in sexual arousal and desire, leading to an increase in libido for both men and women (2)

Rather than acting through a single receptor system, research suggests it may exert modulatory effects across neurotransmitter networks, including GABAergic signaling, opioid receptor activity, and hypothalamicpituitaryadrenal (HPA) axis regulation