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Its activity profile is best understood as systems-level: published in vitro and in vivo work has documented effects on fibroblast proliferation, collagen and growth-factor receptor expression, endothelial migration, nitric oxide system signalling, and dopamine and serotonin pathway markers

Adults over 50, vegetarians and vegans, and people with gastrointestinal issues may need to take vitamin B12 supplements to avoid deficiency

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