doi: 10.1210/jc.2014-3415
If that describes you, the front thigh is a reliable primary site, and your provider can help you assess which works best for your body composition
I did have a bit of a learning curve in the beginning when I was still eating how I previously did, and every time I overate I got nauseous, but that helped me realize I was overeating
I did have side effects to begin with, which was mainly an upset stomach
A similar observation has been reported for another methylenedioxyamphetamine derivative,3,4-methylenedioxyethylamphetamine (MDE) (Kreth et al., n = 6, and *1/*4 n = 3) after two consecutive doses of the drug (Farr et al., *2/*9, *1/*10, *1/*41, *2/*41, *2/*35, *35/*35, and *35/*41 ) displaying an increased induction of plasma hypo-osmolality, hyponatremia, and increased plasma antidiuretic hormone (vasopressin) after MDMA consumption (Aitchison et al., *4/*29, *5/*41, and *6/*41 ) or the IM/IM (*41/*41) genotypes were related to a greater degree of increase in plasma cortisol concentration than the other CYP2D6 after MDMA intake (Wolff et al., The formation of tioether adducts with quinones resulting from the auto-oxidation of the MDMA catechol type metabolites HHMA and HHA (3,4-dihydroxyamphetamine) is one of the hypotheses for MDMA induced neurotoxicity