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Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission

Therefore, glycocalyx damage not only manifests as local pathologic changes in the organ but is also likely to be one of the common pathologic mechanisms for the progression of SAP to MODS

During clinical trials for adjunctive treatment of Lennox-Gastaut syndrome or refractory partial onset seizures in pediatric patients 2 to 16 years of age, persistent decreases in serum bicarbonate occurred in 67% of topiramate-treated patients and 10% of placebo-treated patients

References National Center for Biotechnology Information