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10.1016/j.ebiom.2018.12.034 64 LiuY.-W.LiuW.-H.WuC.-C.JuanY.-C.WuY.-C.TsaiH.-P.et al (2016)

Mitochondria also help regulate calcium, heat production, steroid hormone synthesis, immune signaling, apoptosis, redox balance and the production or metabolism of several important cellular intermediates

Most cytokines and their receptors are expressed by neurons and glial cells throughout development, and several studies have revealed that cytokines play important roles in neurogenesis, synapse formation, and plasticity, including IL-1, IL-6, TNF-, TGF-1 and IFN 326,327,328,329,330,331 Cytokines activate several signal transduction pathways, including the Janus kinase-signal transducer and activation of transcription (JAK-STAT) and PI3K/AKT/mTOR pathways, which regulate numerous cellular responses

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