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BMC Psychiatry 20:499

Check out the latest trends in the May edition of Primes GLP-1 Pipeline Update and the Prime GLP-1 Strategy page for more information

Burks et al[34] has shown that losartan, an inhibitor of the angiotensin II type 1 receptor (AT1), was able to combat disuse atrophy in aged mice that were subjected to hindlimb immobilization, and this protective mechanism was due to an increased activation of the Akt/mTOR pathway