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The organization of the human GSTP1-1 gene promoter and its response to retinoic acid and cellular redox status

Here, we explore the mechanistic interactions, therapeutic implications, and emerging intersections among these machineries, emphasizing novel and thought-provoking insights that expand the current understanding of proteostasis regulation

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After overnight incubation, the medium was changed to 90% of Williams E Medium and supplemented with 12.5% HepaRG preinduction and toxicity medium supplement (Lonza, catalog: MHPIT) and 25 U/mL penicillin-25 g/mL streptomycin, followed by 72 h incubation