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IVF Posts Large Canadian Study Questions Routine ICSI When Male-Factor Infertility Is AbsentA 2026 analysis of more than 140,000 egg-retrieval cycles found that ICSI did not improve cumulative live-birth outcomes over conventional IVF in patients classified as having non-male-factor infertility

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Differences between this trial and earlier studies may reflect variations in patient populations, treatment duration, or study design, including the distinction between prevention and treatment of symptomatic disease

Shen Z, Song J, Yung BC, Zhou Z, Wu A, Chen X