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The FDA has only approved three medications to treat alcohol use disorder: disulfiram, naltrexone, and acamprosate

People on the highest doses of Wegovy ( 2.4 mg , injected weekly), Ozempic ( 2 mg , injected weekly), and Rybelsus ( 14 mg , taken orally daily) tend to experience semaglutide constipation more often than those on lower doses

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Moreover, potential issues related to tolerability (gastrointestinal side effects) and the need for injection in non-oral formulations could impact patient adherence compared to conventional oral PAH therapies