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10.2174/1871527321666220614124145 276 XiaC.ZhouM.DongX.ZhaoY.JiangM.ZhuG.et al (2024)

Too much vitamin B12 intake can cause headache, nausea and vomiting, diarrhea, fatigue, weakness, and tingling

The short answer is a definitive yes

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Answer: The gut hosts a large share of the body's immune tissue, so when the intestinal barrier is compromised the resulting inflammation can show up far from the digestive tract, in joints, skin, energy, and cognition