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The modest sample size and short treatment duration limited the study, according to investigators

Moreover, creating the protocol and model for estimating TMA oxidation is uniquely difficult when nearly all literature data uses a reference initial amount of enzyme, not a continuously produced amount of enzyme such as with our probiotic solution

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Patients with cerebral edema have a high incidence of seizures, but prophylactic antiseizure medications such as phenytoin have not been proven to be beneficial