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Induction of mGlu2 receptors is mediated by acetylation mechanisms that involve transcription factors of the nuclear factor (NF)-B family.

Depression is one of the most prevalent diagnoses in the United States, affecting anywhere from 15 to 20 million people yearly

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By linking endoplasmic reticulum health to the handling of oxidized glutathione, the study suggests that glutathione regulation may be a foundational part of keeping cellular protein production on track

The results were striking: 53.5% of the treated patients achieved a complete response (defined as a reduction in fatigue severity by at least 50%), compared to only 3.5% in the untreated control group