The recommended diluent for reconstitution is Bacteriostatic Water for Injection preserved with benzyl alcohol 0.9%
Peptides arrive in lyophilized powder form for stability, requiring reconstitution with bacteriostatic water before use
HPLC Percentage Equals Clinical Quality Chromatographic area purity does not establish identity, sterility, formulation quality or suitability for administration
40,41 However, most of the prior LAMA studies were conducted in patients with moderate to severe COPD unlike the GOLDEN studies which, as mentioned previously, included a patient population that closely mimicked a real-world COPD population by including very severe patients, those with CV risk, and patients on background LABA
Thus, although GIPR in the AP is required for the weight loss effects of GIPR agonists, it is not the target of therapeutic GIPR antagonists, supporting recent findings that Gipr KO in GABAergic neurons also abolished responses to GIPR agonism but not antagonism 6
