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The comparatively high values for Vss of free cobalamins-(III) are due to the high protein binding of hydroxocobalamin as it reacts in the blood with plasma constituents to form cobalamins-(III) complexes and the rapid distribution of free cobalamins-(III) into tissues

Oral Supplementation Study (2015) A double-blind, placebo-controlled study published in the European Journal of Nutrition gave participants either 250 mg or 1,000 mg of Setria daily for six months

There is also a TUE Pre-Check Form that athletes can submit to get a quick response on whether a TUE is necessary

Intensities of spots for blank and the housekeeping gene peptidylprolyl isomerase A were used for normalization of the data

The free peptide weighs 340 Da