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Individualized program design, including adjustments to intensity and duration, is crucial for optimizing outcomes

Archived from the original on 16 May 2021

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Among oral systemic therapies, methotrexate and acitretin pose the highest hepatotoxic risks, necessitating frequent liver function tests and preventive measures

This activation has been shown to upregulate genes involved in collagen synthesis, cell proliferation, and differentiation while potentially downregulating matrix metalloproteinases