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Encompasses shotgun metagenomic sequencing with functional gene annotation, untargeted metabolomics, bile acid profiling, and transcriptomics
doi: 10.1016/j.cell.2023.10.001 200 EllebrechtCTBhojVGNaceAChoiEJMaoXChoMJet al
GCM-1, glial cell missing-1
LRRK2 is readily detectable in the immortalized mouse RAW264.7 macrophage cell line as well as in primary mouse bone marrow-derived macrophages (BMDMs) [146]
In this study, metabolic signatures were nearly identical between pre-ASD newborns and neurotypical newborns, and differential signatures were observed only in 5-year-olds, suggesting that ASD-associated metabolic signatures develop with age and the maturation of their respective gut microbiota [315]
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