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Western blotting of total cell protein revealed as significant increase in GPx1 protein level when cells were treated with -E2 compared with Se, Se+ -E2 compared with -E2 alone or Se alone (Kruskal-Wallis test, effect of treatment p = 0.005

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Aberrantly activated glial cells exacerbate neuroinflammation and influence synaptic pruning processes, with complement C4-mediated synaptic phagocytosis playing a critical role

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