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doi: 10.1016/j.bbrc.2005.12.011

Consequently, the development of targeted therapies aimed at precisely inhibiting the immunosuppressive functions of MDSCs at specific time points and tissue locations holds promise as a novel and critical strategy for restoring effective immune responses and promoting disease remission (118121)

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These enzymes are the rate-limiting step in the formation of prostanoids (ie, prostaglandins, thromboxane), which are involved in mediating pain and inflammation