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In a 4-year cardiovascular outcomes trial (Trial 7), cholelithiasis was reported in 1.1% of patients treated with RYBELSUS 14 mg and in 0.9% of placebo-treated patients

Basic Res Cardiol (2015) 110(2):6.10.1007/s00395-015-0465-x 8 RathEHallerD

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So, even though emerging evidence looks promising, we still need to go a long way to establish these drugs as safe and effective treatment options for type 1 diabetic patients