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As in PWA mice, such body weight loss was accompanied by a significant decrease in food intake and fat mass (Fig

Other recognized causes of glutathione depletion include malnutrition and sepsis [11], which make patients more susceptible to developing acidosis

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CPT1A can also protect cells from apoptosis by clearing the cytoplasmic long-chain fatty acyl-CoA such as palmitoyl-CoA, and thus impede the production of palmitate/palmitoyl-CoA/ceramide involved in the apoptosis pathway activation 31

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