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Mechanisms of leptin action and leptin resistance

doi: 10.1073/pnas.1908576116 10 LiuYBeyerAAebersoldR

Clinicians should not present DSIP benefits whether framed as DSIP for sleep or otherwise as proven, and should be candid about the wide gap between early signals and clinical proof

The findings indicate that discontinuation rates were significantly higher among patients without type 2 diabetes, with 64.8% stopping treatment within the first year compared with 46.5% of those with diabetes